When it was published, Cryptonomicon was often compared to Pynchon's Gravity's Rainbow, which is also set during WWII and (to a much lesser extent than Cryptonomicon) the present day, has a technology-centered plot (to the extent it has a plot at all), and explores themes of the relationships between individuals, society, and technology.
Calculus and statistics are frequently referred to throughout GR, but especially in the first section, which is set in London during the time that it was being attacked by V2 rockets. In one episode, a statistician works on a mathematical model of the frequency of rocket hits across London. They have divided London into a grid of squares, and counted hits within each square:
But to the likes of employees such as Roger Mexico it is music, not without its majesty, this power series Ne^-m(1 + m + m^2/2! + m^3/3! + ... + m^(n-1)/(n-1)!), terms numbered according to rocket falls per square, the Poisson dispensation ruling not only these annihilations no man can run from, but also cavalry accidents, blood counts, radioactive decay, number of wars per year....
--Viking edition, pp 139–40
The equations that describe the flight of a ballistic missile are brought up frequently -- the title itself refers to the parabola of the missile's flight, and the idea of being on the cusp of some radical change ("a delta-t away") comes up throughout, sometimes in rather poetic ways.
Here's a scene where the main character (to the extent that there is one) is reading up on the V2's technical specs:
So was the Rocket's terrible passage reduced, literally, to bourgeois terms, terms of an equation such as that elegant blend of philosophy and hardware, abstract change and hinged pivots of real metals which describes motion under the aspect of yaw control:
[here follows a multi-term differential equation],
preserving, possessing, steering between Scylla and Charybdis the whole way to Brennschluss.
Other technical matter that comes up throughout involves the engineering of the underground railroad system at the Nordhausen V2 factory; organic chemistry; Pavlovian conditioning of canines, humans, and octopi; and the life expectancy of light bulbs.