Many of Shakespeare's plays were written to be performed by a specific group of actors, the Lord Chamberlain's Men (later called the King's Men), with the result that several famous roles in different plays might have been performed by the same actor. Shakespeare must have known this when writing his plays, so one might guess that he might have included some lines or parts with specific actors in mind, pandering to their particular abilities.
What evidence is there that Shakespeare actually did this, and to what extent?
The essence of this question was posed as part of an exam at the University of Oxford in 1915, as taken by J.R.R. Tolkien. I found it mentioned here and thought it would actually make an interesting question for this site.